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Top Ethereum DeFi Apps by TVL in September 2025: Tether Dominates with $87 Billion Locked

Top Ethereum DeFi Apps by TVL in September 2025: Tether Dominates with $87 Billion Locked

Hey folks, if you're diving into the world of decentralized finance (DeFi) on Ethereum, you've probably heard about Total Value Locked—or TVL for short. It's basically the total amount of assets stashed in a protocol, giving us a snapshot of how much trust and activity it's seeing. Recently, Token Terminal dropped some eye-opening data on the top apps on Ethereum by TVL, and it's a who's who of the DeFi scene as of early September 2025.

Let's break it down. The standout here is Tether, the king of stablecoins, sitting pretty at the top with a whopping $87.2 billion in TVL. That's no surprise—stablecoins like USDT are the backbone of crypto trading and liquidity, keeping things steady amid all the volatility. Right behind it is Aave, a go-to lending platform, with $59 billion locked up. If you're new to this, lending in DeFi means you can earn interest on your crypto without handing it over to a traditional bank—pretty revolutionary, right?

Circle, another stablecoin issuer (think USDC), clocks in at $48.3 billion, showing just how dominant stablecoins are in the Ethereum ecosystem. Then we've got Lido Finance at $37.1 billion, specializing in liquid staking. Staking is like putting your ETH to work to secure the network and earn rewards, but Lido makes it liquid so you can still trade or use it elsewhere.

Sky comes next with $14.7 billion, followed by Ethena at $12.9 billion—both stablecoin players pushing the boundaries of yield generation. Ether.fi is at $12.4 billion with liquid staking, and Pendle rounds out the top eight at $9.6 billion, focusing on asset management through yield tokenization. That's a fancy way of saying it lets you trade future yields separately from the principal—super useful for advanced strategies.

Diving deeper, Spark at $7.2 billion is another lending protocol, Morpho at $7.1 billion optimizes lending markets, and Uniswap, the OG decentralized exchange (DEX), holds $4.9 billion. Uniswap lets you swap tokens peer-to-peer without intermediaries, a core piece of DeFi. Maple Finance follows at $3.5 billion for lending, Compound at $3 billion (another lending classic), Rocket Pool at $2.8 billion for liquid staking, Fluid at $2.7 billion lending, Curve at $2.3 billion DEX, and Securitize at $2.1 billion in infrastructure.

Table of top Ethereum DeFi apps by TVL including Tether, Aave, Circle, and more

This data underscores Ethereum's dominance in DeFi, even with competition from faster chains like Solana or Tron. As Token Terminal's post quotes, Ethereum hosts around $330 billion in total TVL across all apps—way ahead of the pack. For meme token hunters and blockchain practitioners, keeping an eye on these TVL shifts can signal where liquidity is flowing, potentially spotting opportunities in emerging protocols or even meme-integrated DeFi plays.

If you're building or investing in the space, tools like DefiLlama can help track these metrics in real-time. What's your take on Tether's lead? Is it sustainable, or will yield-bearing stablecoins like Ethena shake things up? Drop your thoughts below—we're all about that community vibe here at Meme Insider.

Stay tuned for more updates on meme tokens, DeFi trends, and everything blockchain. Whether you're a newbie or a pro, our knowledge base has got you covered to level up your game.

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